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TEAD-IN-1

TEAD-IN-1 (Compound 2) is a potent inhibitor of TEAD auto-palmitoylation (IC50 = 603 nM) . It disrupts the YAP-TEAD oncogenic interaction while promoting TEAD-VGLL4 binding, making it a valuable chemical probe for Hippo pathway and cancer research in both cellular and animal models.

Product Specifications

CAS Number

2412761-57-8

Field of Research

Stem Cell & Developmental Biology

Smiles

C (=C/C1CCC (F) (F) CC1) \C2=C (OC) N=CC (NS (C) (=O) =O) =C2

Molecular Formula

C15H20F2N2O3S

Molecular Weight

346.393

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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