TEAD-IN-1
TEAD-IN-1 (Compound 2) is a potent inhibitor of TEAD auto-palmitoylation (IC50 = 603 nM) . It disrupts the YAP-TEAD oncogenic interaction while promoting TEAD-VGLL4 binding, making it a valuable chemical probe for Hippo pathway and cancer research in both cellular and animal models.
Product Specifications
CAS Number
2412761-57-8
Field of Research
Stem Cell & Developmental Biology
Smiles
C (=C/C1CCC (F) (F) CC1) \C2=C (OC) N=CC (NS (C) (=O) =O) =C2
Molecular Formula
C15H20F2N2O3S
Molecular Weight
346.393
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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