E3 ligase Ligand 46
E3 ligase Ligand 46 is a cereblon (CRBN) -binding molecule utilized as a key component in constructing PROTAC degraders, such as SMARCA2/4 degrader-36. It enables targeted protein degradation, a technique widely applied in oncology and chemical biology research for probing protein function in vitro.
Product Specifications
CAS Number
3033591-48-6
Field of Research
Molecular Biology, Pharmacology & Drug Discovery
Smiles
C ([C@@H] (N=[N+]=[N-]) C (C) C) (=O) N1[C@H] (C (N[C@@H] (C) C2=CC=C (C=C2) C3=C (C) N=CS3) =O) C[C@@H] (O) C1
Molecular Formula
C22H28N6O3S
Molecular Weight
456.561
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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