EGFR-IN-148
EGFR-IN-148 (compound 8c) is a potent small molecule EGFR inhibitor exhibiting an IC50 of 0.161 μM. In vitro studies, such as those using HepG2 cells, demonstrate its ability to induce G1/S phase cell cycle arrest and promote apoptosis, supporting its application in cancer research.
Product Specifications
Field of Research
Cardiovascular Research, Cell Biology, Signal Transduction
Smiles
COC1=CC2=C (C=C1) NC (=O) C (=C2) /C=N/NC3=CC=C (C=C3) S (=O) (=O) N
Molecular Formula
C17H16N4O4S
Molecular Weight
372.398
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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