SH514
SH514 is a specific IRF4 inhibitor (IC50 = 2.63 μM) that binds the IRF4 DNA-binding domain, blocking its transcriptional activity and downregulating key oncogenic targets like MYC and Blimp1. It is a valuable chemical probe for studying multiple myeloma pathogenesis and treatment in both cellular and animal models.
Product Specifications
Product Name Alternative
SH 514
Field of Research
Immunology & Inflammation
Solubility
10% DMSO+90% Corn Oil:3.3 mg/mL (6.41 mM) ; DMSO:80 mg/mL (155.44 mM)
Smiles
C[C@@H] ([C@H]1CC[C@@H]2[C@@]1 (CC[C@H]3[C@H]2C (=O) C=C4[C@@]3 (C=C (C (=O) C4 (C) C) C#N) C) C) C (=O) NC5=CC=C (C=C5) OC
Molecular Formula
C32H38N2O4
Molecular Weight
514.66
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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