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VEGFR-2-IN-61

VEGFR-2-IN-61 (Compound 7b) is a small molecule VEGFR-2 inhibitor with an IC50 of 2.83 μM. It demonstrates anti-cancer activity in vitro by inhibiting MCF-7 cell proliferation (IC50=2.12 μM), suppressing migration, and inducing oxidative stress and apoptosis, supporting its use in angiogenesis and oncology research.

Product Specifications

Field of Research

Cardiovascular Research, Cardiovascular Research; Cell Biology, Cell Biology, Immunology & Inflammation, Metabolism Research, Signal Transduction

Smiles

CC (C) C1=CC=C (C=C1) NC (=O) C2=C (N (N=C2C3=CNC4=CC=CC=C43) C5=CC=CC=C5) N

Molecular Formula

C27H25N5O

Molecular Weight

435.52

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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