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CZY43

CZY43 is a potent and selective HER3 degrader that induces dose- and time-dependent HER3 degradation in SKBR3 breast cancer cells. It effectively suppresses downstream oncogenic signaling and inhibits cell proliferation, demonstrating superior activity to Bosutinib in vitro.

Product Specifications

Field of Research

Cardiovascular Research, Signal Transduction

Smiles

COC1=C (C=C2C (=C1) C (=C (C=N2) C#N) NC3=CC (=C (C=C3Cl) Cl) OC) OCCCN4CCC5 (CC4) CCN (CC5) CCC67CC8CC (C6) CC (C8) C7

Molecular Formula

C42H53Cl2N5O3

Molecular Weight

746.808

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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