CZY43
CZY43 is a potent and selective HER3 degrader that induces dose- and time-dependent HER3 degradation in SKBR3 breast cancer cells. It effectively suppresses downstream oncogenic signaling and inhibits cell proliferation, demonstrating superior activity to Bosutinib in vitro.
Product Specifications
Field of Research
Cardiovascular Research, Signal Transduction
Smiles
COC1=C (C=C2C (=C1) C (=C (C=N2) C#N) NC3=CC (=C (C=C3Cl) Cl) OC) OCCCN4CCC5 (CC4) CCN (CC5) CCC67CC8CC (C6) CC (C8) C7
Molecular Formula
C42H53Cl2N5O3
Molecular Weight
746.808
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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