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Dual Galectin-3/EGFR-IN-1

Dual Galectin-3/EGFR-IN-1 (Compound 29) is a dual-target inhibitor with K_D values of 52.29 μM for Galectin-3 and 3.31 μM for EGFR. It demonstrates antifibrotic effects by suppressing TGF-β-induced hepatic stellate cell activation and inducing apoptosis in LX-2 cells, showing potential for liver fibrosis research.

Product Specifications

Field of Research

Cardiovascular Research, Cell Biology, Immunology & Inflammation, Signal Transduction

Smiles

CC (=O) NC1C (C (C (OC1OCCN2C=C (N=N2) C3=CC (=CC=C3) NC4=NC=NC5=CC (=C (C=C54) OCCOC) OCCOC) CO) O) O

Molecular Formula

C32H41N7O10

Molecular Weight

683.709

Storage Conditions

-20°C

Notes

For research use only.

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