DDO-02267
DDO-02267 is a potent, selective covalent inhibitor of the RNA demethylase ALKBH5 (IC50 = 0.49 μM) . It elevates m6A levels and disrupts the ALKBH5-AXL signaling axis, serving as a valuable chemical probe for studying m6A biology in both cellular and in vivo research contexts.
Product Specifications
CAS Number
2919768-58-2
Field of Research
Cardiovascular Research, Metabolism Research, Signal Transduction
Smiles
O=CC=1C=C (C=2C=CC=CC2C1O) S (=O) (=O) NC (=O) C3=NC=CC (=C3) C (=O) O
Molecular Formula
C18H12N2O7S
Molecular Weight
400.362
Storage Conditions
-20°C
Notes
For research use only.
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