GluN2A Allosteric modulator 1
GluN2A Allosteric Modulator 1 (Compound 11) is an orally active, brain-penetrant, and highly selective negative allosteric modulator of GluN2A-containing NMDA receptors (IC50 = 42 nM) . Its selectivity over GluN2B (>300-fold) makes it a valuable research tool for investigating the specific roles of GluN2A in neurological disorders, supporting both in vitro and in vivo studies.
Product Specifications
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Smiles
ClC1=CC=CC (C (F) (F) COC2=NC=C (C (NC3 (C4=CN=CC=N4) CC3) =O) N=C2) =C1
Molecular Formula
C20H16ClF2N5O2
Molecular Weight
431.823
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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