ARN23765
ARN23765 is a potent F508del-CFTR corrector (EC50 = 38 pM) that rescues mutant protein maturation and membrane function. It is a valuable research tool for investigating CFTR pharmacology and cystic fibrosis disease mechanisms in both cellular and animal models.
Product Specifications
CAS Number
2244458-40-8
Field of Research
Pharmacology & Drug Discovery
Smiles
O ([C@@H]1C=2N (N=C (C (F) (F) F) C2CCC1) C3=CC (C (N (C) C=4C=C5C (=CC4) OC (F) (F) O5) =O) =CC=C3) C6=CC=C (C (O) =O) C=C6
Molecular Formula
C30H22F5N3O6
Molecular Weight
615.504
Storage Conditions
-20°C
Notes
For research use only.
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