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PROTAC ROR1 degrader-1

PROTACROR1degrader-1 (Compound 11d) is a bifunctional PROTAC molecule that selectively targets and degrades the pseudokinase ROR1 with a DC50 of 40-80 nM in NSCLC cells. It induces apoptosis and PARP cleavage in NCI-H23 cells, making it a valuable chemical tool for studying ROR1 biology and targeted protein degradation in cancer research.

Product Specifications

Field of Research

Cell Biology, Metabolism Research, Pharmacology & Drug Discovery, Stem Cell & Developmental Biology

Molecular Formula

C55H74BrN11O5S

Molecular Weight

1081.22

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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