PROTAC ROR1 degrader-1
PROTACROR1degrader-1 (Compound 11d) is a bifunctional PROTAC molecule that selectively targets and degrades the pseudokinase ROR1 with a DC50 of 40-80 nM in NSCLC cells. It induces apoptosis and PARP cleavage in NCI-H23 cells, making it a valuable chemical tool for studying ROR1 biology and targeted protein degradation in cancer research.
Product Specifications
Field of Research
Cell Biology, Metabolism Research, Pharmacology & Drug Discovery, Stem Cell & Developmental Biology
Molecular Formula
C55H74BrN11O5S
Molecular Weight
1081.22
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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