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PPARγ modulator-2

PPARγ modulator-2 (Compound (R) -2n) is a potent and reversible inhibitor of the PPARγ ligand-binding domain (IC50 = 41 nM) . This small molecule demonstrates antidiabetic effects in vitro and in vivo, including improved glucose tolerance and insulin sensitivity in db/db mouse models, supporting metabolic disease research.

Product Specifications

CAS Number

2897652-01-4

Field of Research

Metabolism Research, Molecular Biology

Smiles

O=S (=O) (OC=1C=CC (=CC1) S2 (=O) =N[Se]C=3C=C (OS (=O) (=O) C4=CC=C (C=C4) C) C=CC32) C5=CC=C (C=C5) C

Molecular Formula

C26H21NO7S3Se

Molecular Weight

634.6

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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