WR-S-462
WR-S-462 is a potent and selective STAT3 inhibitor with a Kd of 58 nM, blocking STAT3 phosphorylation, nuclear translocation, and downstream target gene expression. It demonstrates in vitro efficacy against TNBC cell growth and metastasis and is a valuable tool for oncology research, particularly in studying STAT3-driven cancer pathways.
Product Specifications
Field of Research
Cell Biology, Signal Transduction, Stem Cell & Developmental Biology
Molecular Formula
C24H22N4O4S
Molecular Weight
462.52
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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