PBA-1105 TFA
PBA-1105 TFA is an AUTOTAC molecule that selectively targets misfolded proteins by binding their hydrophobic regions, inducing p62 self-oligomerization to drive their autophagic degradation. It enhances clearance of Ub-bound aggregates and is a valuable research tool for studying autophagy mechanisms in cellular and in vivo models of protein aggregation diseases.
Product Specifications
Field of Research
Cell Biology, Immunology & Inflammation, Pharmacology & Drug Discovery
Smiles
C1=CC=C (C=C1) CCCC (=O) NCCOCCOCCOCCNCC2=CC (=C (C=C2) OCC3=CC=CC=C3) OCC4=CC=CC=C4.C (=O) (C (F) (F) F) O
Molecular Formula
C41H49F3N2O8
Molecular Weight
754.832
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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