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OBI-992 drug-linker

OBI-992 drug-linker is a conjugate of the topoisomerase I inhibitor Exatecan and a cleavable linker, designed for constructing antibody-drug conjugates (ADCs) . It has shown potent antitumor efficacy in mouse xenograft models, supporting its application in ADC research and development for targeted cancer therapy.

Product Specifications

CAS Number

3039487-10-7

Smiles

N (C (OCC1=CC=C (NC ([C@@H] (NC ([C@@H] (NC (CC[C@H] (NC (=O) C2CCC (CN3C (=O) C=CC3=O) CC2) C (NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC) =O) =O) C (C) C) =O) C) =O) C=C1) =O) [C@@H]4C5=C6C (C=7N (C6) C (=O) C8=C (C7) [C@] (CC) (O) C (=O) OC8) =NC=9C5=C (CC4) C (C) =C (F) C9

Molecular Formula

C106H162FN9O37

Molecular Weight

2173.46

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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