OBI-992 drug-linker
OBI-992 drug-linker is a conjugate of the topoisomerase I inhibitor Exatecan and a cleavable linker, designed for constructing antibody-drug conjugates (ADCs) . It has shown potent antitumor efficacy in mouse xenograft models, supporting its application in ADC research and development for targeted cancer therapy.
Product Specifications
CAS Number
3039487-10-7
Smiles
N (C (OCC1=CC=C (NC ([C@@H] (NC ([C@@H] (NC (CC[C@H] (NC (=O) C2CCC (CN3C (=O) C=CC3=O) CC2) C (NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC) =O) =O) C (C) C) =O) C) =O) C=C1) =O) [C@@H]4C5=C6C (C=7N (C6) C (=O) C8=C (C7) [C@] (CC) (O) C (=O) OC8) =NC=9C5=C (CC4) C (C) =C (F) C9
Molecular Formula
C106H162FN9O37
Molecular Weight
2173.46
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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