P38 Kinase inhibitor 7
P38 Kinase inhibitor 7 (Comp:XXXIX) is a potent and selective p38α inhibitor with an IC50 of 5.25 nM. It effectively blocks TNFα production in THP-1 cells (IC50 = 5.88 nM), making it a valuable tool for researching inflammation and autoimmune diseases in cellular models.
Product Specifications
CAS Number
815595-14-3
Field of Research
Pharmacology & Drug Discovery, Signal Transduction
Smiles
FC1=CC=C (C=C1) C=2N=C3OC=CN3C2C=4N=C (N=CC4) NCC (C) (C) CN (C) C
Molecular Formula
C22H25FN6O
Molecular Weight
408.472
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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