SJ44236
SJ44236 is a potent and orally bioavailable BET PROTAC degrader targeting BRD2/3/4. It exhibits nanomolar cytotoxicity in leukemia and medulloblastoma cell lines by downregulating c-Myc and upregulating p53. This molecule is a useful chemical probe for studying BET protein function in cancer research and PROTAC mechanisms.
Product Specifications
Field of Research
Epigenetics & Chromatin, Pharmacology & Drug Discovery
Molecular Formula
C40H45ClN8O3S
Molecular Weight
753.36
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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