YW-N-7 TFA
YW-N-7 (TFA) is a potent RET-targeting PROTAC degrader with a DC50 of 88 nM. It effectively inhibits RET kinase activity and demonstrates robust antitumor efficacy in KIF5B-RET xenograft models, supporting its use in oncology research for studying RET-driven cancers both in vitro and in vivo.
Product Specifications
Field of Research
Cell Biology, Immunology & Inflammation, Pharmacology & Drug Discovery, Signal Transduction
Molecular Formula
C58H63F3N12O9
Molecular Weight
1129.19
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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