YW-N-7 TFA

YW-N-7 (TFA) is a potent RET-targeting PROTAC degrader with a DC50 of 88 nM. It effectively inhibits RET kinase activity and demonstrates robust antitumor efficacy in KIF5B-RET xenograft models, supporting its use in oncology research for studying RET-driven cancers both in vitro and in vivo.