Wnt pathway inhibitor 5

Compound 28 (Wntpathway inhibitor 5) is a potent small molecule Wnt pathway inhibitor with sub-nanomolar activity (IC50 < 0.003 μM) . It is utilized in cancer research, demonstrating efficacy in vitro and in vivo against models including breast cancer, osteosarcoma, and head and neck squamous cell carcinoma.