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E3 Ligase Ligand-linker Conjugate 170

Compound I (E3 Ligase Ligand-linker Conjugate 170) is a versatile building block for PROTAC synthesis. It exhibits potent in vitro antiproliferative activity against SU-DHL-4 non-Hodgkin's lymphoma cells, with an IC50 below 0.2 μM, supporting targeted protein degradation research.

Product Specifications

CAS Number

2379572-21-9

Field of Research

Molecular Biology, Pharmacology & Drug Discovery

Smiles

O=C1NC (=O) C (N2C (=O) C=3C=CC=C (NCC4=CC=C (C=C4F) CN5CC (N6CCOCC6) C5) C3C2=O) CC1

Molecular Formula

C28H30FN5O5

Molecular Weight

535.567

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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