CTT2274
CTT2274 is a PSMA-targeted prodrug of MMAE, utilizing a pH-sensitive phosphoramidate linker for selective payload delivery. It is applied in prostate cancer research, demonstrating antitumor activity in both in vitro cytotoxicity assays and in vivo xenograft models.
Product Specifications
Field of Research
Immunology & Inflammation
Smiles
CC[C@H] (C) [C@@H] ([C@@H] (CC (=O) N1CCC[C@H]1[C@@H] ([C@@H] (C) C (=O) N[C@H] (C) [C@H] (C2=CC=CC=C2) O) OC) OC) N (C) C (=O) [C@H] (C (C) C) NC (=O) [C@H] (C (C) C) N (C) C (=O) OCC3=CC=C (C=C3) OC (=O) N (C) CCN (C) P (=O) (O) OCC[C@@H] (C (=O) O) NC (=O) C4=CC=C (C=C4) CN5C6=C (C7=CC=CC=C7N (CC8=CC=CC=C86) C (=O) CCC (=O) N[C@@H] (CC9=CC=C (C=C9) C1=CC=CC=C1) C (=O) NCCCCCC (=O) N[C@@H] (CCC (=O) N[C@@H] (CCCOP (=O) (N[C@@H] (CCC (=O) O) C (=O) O) O) C (=O) O) C (=O) O) N=N5
Molecular Formula
C119H159N17O33P2
Molecular Weight
2417.58
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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