VK13
VK13 (Compound 6) is a dual-target inhibitor with potent activity against human cathepsin L (Ki=2.6 nM) and SARS-CoV-2 3CL protease (Ki=0.55 nM), also demonstrating antiviral efficacy against SARS-CoV-2 in cellular assays (EC50=1.25 μM) . This compound is a valuable research tool for studying coronavirus replication and host protease functions in vitro.
Product Specifications
Field of Research
Infectious Disease & Virology, Protein Biochemistry
Smiles
CC (C) C[C@@H] (C (=O) N[C@@H] (CC1=CC=CNC1=O) C=O) NC (=O) C2=CC3=C (N2) C=CC=C3OC
Molecular Formula
C24H28N4O5
Molecular Weight
452.503
Storage Conditions
-20°C
Notes
For research use only.
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