TRPV1-IN-3
TRPV1-IN-3 (compound 14) is a potent TRPV1 inhibitor used in pulmonary fibrosis research. It exhibits antifibrotic effects in vitro (IC50 = 0.51 μM) by suppressing TGF-β/Smads and MAPK signaling. In vivo, it reduces lung collagen deposition, improves alveolar structure, and enhances survival in a Bleomycin-induced mouse model of idiopathic pulmonary fibrosis.
Product Specifications
CAS Number
87657-67-8
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Smiles
C (=C/C (CCCCC1=CC=CC=C1) =O) \C2=CC (O) =C (O) C=C2
Molecular Formula
C19H20O3
Molecular Weight
296.36
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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