AZ3246
AZ3246 is a potent and selective oral HPK1 inhibitor with sub-3 nM IC50, promoting IL-2 secretion in T cells (EC50 = 90 nM) . This low-clearance compound is utilized in immuno-oncology research to study T-cell activation and antitumor responses in both cellular and in vivo models.
Product Specifications
CAS Number
2893978-54-4
Field of Research
Immunology & Inflammation, Signal Transduction
Smiles
O=C (N) C1=NC (=C (N=C1NC2=CN (N=C2C) CC (F) (F) F) C3CC3) C4=CN=CC5=C4N=CN5C
Molecular Formula
C21H20F3N9O
Molecular Weight
471.438
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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