TGF-βRI inhibitor 3
Compound 9ac (TGF-βRI inhibitor 3) is a selective TGF-β pathway inhibitor with IC50 values of 0.63 μM for ALK5 and 13 μM for c-Src kinase. This tool compound is used in vitro to study fibrotic diseases, cancer metastasis, and EMT within TGF-β signaling research.
Product Specifications
CAS Number
666729-57-3
Field of Research
Cardiovascular Research, Pharmacology & Drug Discovery, Signal Transduction, Stem Cell & Developmental Biology
Smiles
O=C (C=1C=C (C (=CC1OC=2C=CN=C3C=C (OC) C (OC) =CC32) C) C) C
Molecular Formula
C21H21NO4
Molecular Weight
351.396
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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