AUR1545
AUR1545 is a selective degrader of KAT2A/KAT2B with demonstrated inhibitory activity in cancer models including AML, SCLC, and NEPC. It has shown efficacy in suppressing tumor growth in the NCI-H1048 xenograft model, supporting its use in oncology research for both in vitro and in vivo studies.
Product Specifications
CAS Number
3031593-79-7
Product Name Alternative
AUR 1545
Field of Research
Epigenetics & Chromatin
Purity
98.84% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween-80+45% Saline:5 mg/mL (6.03 mM) ; DMSO:80 mg/mL (96.53 mM)
Smiles
O=C1C=2C (CN1C3C (=O) NC (=O) CC3) =CC (=CC2) N4CCN (CC5CCN (C (=O) C6=CC=C (C=C6) [C@H]7C[C@@H] (NC8=C (Br) C (=O) N (C) N=C8) CN (C) C7) CC5) CC4
Molecular Formula
C41H50BrN9O5
Molecular Weight
828.8
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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