Antidepressant agent 8
Compound 1f is a selective GluN1/2A NMDA receptor antagonist (IC50 = 2.94 μM) with demonstrated blood-brain barrier permeability. It exhibits antidepressant-like activity in a zebrafish depression model, supporting its utility in neuroscience research for studying NMDA receptor function and depression pathophysiology.
Product Specifications
CAS Number
3066104-04-6
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Smiles
O=C (NCC1CCCCC1) CSC2=NN=C (S2) NCC=3C=CC=C (F) C3
Molecular Formula
C18H23FN4OS2
Molecular Weight
394.53
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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