PDHK1-IN-1
PDHK1-IN-1 (compound 17) is a selective PDHK1 inhibitor (IC50 = 1.5 μM) that blocks phosphorylation of PDC E1α at Ser232 and Ser293, reversing PDHK1-mediated suppression of oxidative metabolism. This tool compound is used in cancer metabolism research to study the Warburg effect and has demonstrated anticancer properties in cellular assays.
Product Specifications
Field of Research
Metabolism Research
Molecular Formula
C14H11BrClNO4S
Molecular Weight
404.66
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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