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GJG057

GJG057 is a potent and selective oral inhibitor of Leukotriene C4 synthase (LTC4S), demonstrating an IC50 of 44 nM in human whole blood. It shows anti-inflammatory efficacy in murine asthma models, supporting its research use in studying allergic inflammation pathways in both in vitro and in vivo settings.

Product Specifications

CAS Number

2761767-18-2

Product Name Alternative

GJG-057

Field of Research

Metabolism Research

Purity

99.80% (May vary between batches)

Solubility

DMSO:40 mg/mL (87.64 mM)

Smiles

O=C1N (C2=CC=C (F) C (F) =C2) C3 (CCN (C=4N=CN=C (OCC (F) (F) F) C4) CC3) CCC1

Molecular Formula

C21H21F5N4O2

Molecular Weight

456.41

Storage Conditions

-20°C

Notes

For research use only.

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