KRASG12C IN-16
KRASG12C IN-16 (SK-17) is an orally bioavailable, selective covalent inhibitor of the KRASG12C mutant. It demonstrates antitumor activity by inducing apoptosis and suppressing MAPK and PI3K/mTOR signaling, as shown in in vitro and in vivo models of pancreatic cancer research.
Product Specifications
Field of Research
Cell Biology, Pharmacology & Drug Discovery, Signal Transduction
Molecular Formula
C28H35ClN8O2
Molecular Weight
551.08
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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