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BAY-277

BAY-277 is a potent and selective small molecule degrader of methionine aminopeptidase 2 (METAP2), demonstrating high inhibitory activity with IC50 values of approximately 5.8 nM and 5.9 nM against the human and mouse enzymes, respectively. This compound serves as a valuable research tool for investigating METAP2's role in angiogenesis and tumor biology in both cellular and animal models.

Product Specifications

Field of Research

Metabolism Research

Molecular Formula

C44H52N8O5

Molecular Weight

772.93

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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