(S) -WSD0628
(S) -WSD0628 is the stereochemically pure S-enantiomer of the ATM kinase inhibitor WSD0628. It potently inhibits ATM autophosphorylation in vitro (IC50 < 100 nM in MCF-7 cells), exhibits radiosensitizing properties, and demonstrates blood-brain barrier penetration, supporting its research use in oncology and DNA damage response studies.
Product Specifications
CAS Number
2765449-10-1
Field of Research
Molecular Biology, Signal Transduction
Smiles
O=C1N (C=2C=3C (N=CC2N1C) =CC=C (C3) C=4C=CC (OC) =NC4) [C@@H]5C (F) (F) CN (C) CC5
Molecular Formula
C23H23F2N5O2
Molecular Weight
439.458
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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