Tubulin polymerization-IN-77
Tubulin polymerization-IN-77 (Compound 15c) is a brain-penetrant microtubule-destabilizing agent with potent anti-glioblastoma activity. It blocks cell cycle progression at G2/M phase, inhibits tumor cell migration, and induces apoptosis in vitro, demonstrating potential for neuro-oncology research.
Product Specifications
CAS Number
3023350-32-2
Field of Research
Cell Biology, Signal Transduction
Smiles
O (C) C=1C=2[C@@] (N (C (F) (F) F) CCC2C (Br) =C3C1OCO3) ([C@@]4 (C=5C (C (=O) O4) =C (OC) C (OC) =CC5) [H]) [H]
Molecular Formula
C22H19BrF3NO7
Molecular Weight
546.288
Storage Conditions
-20°C
Notes
For research use only.
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