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Tubulin polymerization-IN-77

Tubulin polymerization-IN-77 (Compound 15c) is a brain-penetrant microtubule-destabilizing agent with potent anti-glioblastoma activity. It blocks cell cycle progression at G2/M phase, inhibits tumor cell migration, and induces apoptosis in vitro, demonstrating potential for neuro-oncology research.

Product Specifications

CAS Number

3023350-32-2

Field of Research

Cell Biology, Signal Transduction

Smiles

O (C) C=1C=2[C@@] (N (C (F) (F) F) CCC2C (Br) =C3C1OCO3) ([C@@]4 (C=5C (C (=O) O4) =C (OC) C (OC) =CC5) [H]) [H]

Molecular Formula

C22H19BrF3NO7

Molecular Weight

546.288

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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