Dactinomycin
Dactinomycin D (Actinomycin IV) is an antibiotic and autophagy activator produced by Streptomyces bacteria fermentation, which inhibits transcription and replication by inserting into the DNA double helix, and can also promote p53 phosphorylation and accumulation through MDM2 overexpression, serving as a chemotherapy drug for cancer treatment.
Product Specifications
CAS Number
50-76-0
Product Name Alternative
Actinomycin IV, Dactinomycin D
Field of Research
Cell Biology, Infectious Disease & Virology, Molecular Biology, Pharmacology & Drug Discovery
Purity
99.33% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween-80+45% Saline:3.3 mg/mL (2.63 mM) ; DMSO:80 mg/mL (63.72 mM)
Smiles
Molecular Formula
C62H86N12O16
Molecular Weight
1255.42
Storage Conditions
Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Notes
For research use only.
Available Sizes
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