Dactinomycin

Dactinomycin D (Actinomycin IV) is an antibiotic and autophagy activator produced by Streptomyces bacteria fermentation, which inhibits transcription and replication by inserting into the DNA double helix, and can also promote p53 phosphorylation and accumulation through MDM2 overexpression, serving as a chemotherapy drug for cancer treatment.

Product Specifications

CAS Number

50-76-0

Product Name Alternative

Actinomycin IV, Dactinomycin D

Field of Research

Cell Biology, Infectious Disease & Virology, Molecular Biology, Pharmacology & Drug Discovery

Purity

99.33% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween-80+45% Saline:3.3 mg/mL (2.63 mM) ; DMSO:80 mg/mL (63.72 mM)

Smiles

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