ARN-6039
ARN-6039 is an orally available inverse agonist of RORγ for autoimmune demyelinating disease.
Product Specifications
CAS Number
[1675206-11-7]
Product Name Alternative
PF 00477736
UNSPSC
12352005
Target
ROR
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/arn-6039.html
Solubility
10 mM in DMSO
Smiles
COC1=C(C=C(C2=C1)CC(C2=O)CC3=NC=CC=C3C(F)(F)F)N4CCOCC4
Molecular Formula
C21H21F3N2O3
Molecular Weight
406.40
References & Citations
[1]Vankayalapati, Hariprasad; Yerramreddy, Venkatakrishnareddy. Preparation of dihydroindenone derivatives for use as retinoic acid-related orphan nuclear receptor modulators. US20150072980A1
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 1
Available Sizes
Curated Selection
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