E3 ligase Ligand 48
PROTACAR Degrader-9 (Compound c6) is a CRBN-based PROTAC that selectively degrades the androgen receptor (AR) . It demonstrates potent activity in vitro, degrading AR in human dermal papilla cells with a DC50 of 262.38 nM, making it a valuable tool for prostate cancer and androgenetic alopecia research.
Product Specifications
Field of Research
Molecular Biology, Pharmacology & Drug Discovery
Smiles
C1CC (CN (C1) C2=CC=C (C=C2) C (=O) NC3CCC (=O) NC3=O) C=O
Molecular Formula
C18H21N3O4
Molecular Weight
343.377
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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