DGKζ-IN-10
DGKζ-IN-10 (compound 349) is a potent and selective small molecule inhibitor of diacylglycerol kinase zeta (DGKζ), exhibiting an IC50 value of ≤200 nM. This tool compound enables the study of DGKζ's role in immune cell signaling, T-cell anergy, and cancer biology in both cellular and biochemical assays.
Product Specifications
CAS Number
3062708-86-2
Smiles
N ([C@@H] (C (N) =O) C) (C=1SC (C (=O) C=2C=CC (=NC2) C3=CC=CC=C3) =C (N) N1) C4=CC=C (F) C=C4
Molecular Formula
C24H20FN5O2S
Molecular Weight
461.511
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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