Proteasome-IN-6
Proteasome-IN-6 (J-80) is a potent and selective inhibitor of the Trypanosoma brucei proteasome β5 subunit, demonstrating low nanomolar efficacy against major subspecies in vitro and antitrypanosomal activity in a mouse model, supporting its use for researching novel anti-sleeping sickness therapeutics.
Product Specifications
CAS Number
3063720-23-7
Field of Research
Infectious Disease & Virology, Protein Biochemistry
Smiles
CCCCCC (=O) N[C@H] (CC (=O) N (CC) CC) C (=O) N[C@@H] (CC1=CC=C (C=C1) F) C (=O) N[C@@H] (CC2=C (C=C (C=C2) F) F) C (=O) [C@]3 (CO3) C
Molecular Formula
C35H45F3N4O6
Molecular Weight
674.75
Storage Conditions
-20°C
Notes
For research use only.
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