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Proteasome-IN-6

Proteasome-IN-6 (J-80) is a potent and selective inhibitor of the Trypanosoma brucei proteasome β5 subunit, demonstrating low nanomolar efficacy against major subspecies in vitro and antitrypanosomal activity in a mouse model, supporting its use for researching novel anti-sleeping sickness therapeutics.

Product Specifications

CAS Number

3063720-23-7

Field of Research

Infectious Disease & Virology, Protein Biochemistry

Smiles

CCCCCC (=O) N[C@H] (CC (=O) N (CC) CC) C (=O) N[C@@H] (CC1=CC=C (C=C1) F) C (=O) N[C@@H] (CC2=C (C=C (C=C2) F) F) C (=O) [C@]3 (CO3) C

Molecular Formula

C35H45F3N4O6

Molecular Weight

674.75

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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