MS8511 hydrochloride
MS8511 hydrochloride is a covalent, irreversible inhibitor selectively targeting G9a and GLP histone methyltransferases (IC50s: 100 nM and 140 nM) . It effectively diminishes H3K9me2 levels and demonstrates anti-proliferative effects, supporting its use in epigenetic cancer research both in vitro and in vivo.
Product Specifications
CAS Number
3031788-28-7
Product Name Alternative
MS8511 HCl, MS-8511 HCl, MS-8511 hydrochloride
Field of Research
Epigenetics & Chromatin
Purity
99.24% (May vary between batches)
Solubility
Methanol:24 mg/mL (45.1 mM)
Smiles
Cl.O=C (C=C) NC=1N=C2C=C (OCCCN3CCCC3) C (OC) =CC2=C (C1) NC4CCN (CC4) C (C) C
Molecular Formula
C28H42ClN5O3
Molecular Weight
532.12
Storage Conditions
-20°C
Notes
For research use only.
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