Tubulin polymerization-IN-73
Tubulin polymerization-IN-73 is a microtubule polymerization inhibitor (IC50 = 1.8 μM) that induces G2/M phase arrest and apoptosis in A549 cells. It demonstrates potent antiproliferative activity against both wild-type and resistant A549 cell lines and has shown antitumor efficacy in mouse models, supporting its use in cancer research.
Product Specifications
CAS Number
3077842-16-8
Field of Research
Cell Biology, Signal Transduction
Smiles
COC1=C (C=C (C=C1) C2=CC (=C3C (=C2) NC=N3) C4=C (C (=C (C=C4) OC) OC) OC) N
Molecular Formula
C23H23N3O4
Molecular Weight
405.446
Storage Conditions
-20°C
Notes
For research use only.
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