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PI3Kδ/BET-IN-1

PI3Kδ/BET-IN-1 (compound 10b) is a potent dual inhibitor of PI3Kδ (IC50=112 nM) and BRD4-BD1 (IC50=19 nM) . It demonstrates robust antiproliferative activity in DLBCL cell models, supporting its investigation in hematological cancer research and targeted therapy development.

Product Specifications

CAS Number

3054869-10-9

Field of Research

Epigenetics & Chromatin, Signal Transduction

Smiles

O=C1C=2NC=CC2C (=CN1C) C3=NC=4C=C (SC4C (=N3) N5CCOCC5) CN6CCC (CC6) C (O) (C) C

Molecular Formula

C27H34N6O3S

Molecular Weight

522.662

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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