CG-3-246
CG-3-246 is a potent small molecule dual inhibitor of FLT3 (Kd=63 nM) and BCL-2 (Kd=4.25 nM) . It is a valuable research tool for studying acute myeloid leukemia (AML), demonstrating activity in both cellular assays and in vivo models of the disease.
Product Specifications
CAS Number
3107307-79-6
Field of Research
Cardiovascular Research, Cell Biology, Signal Transduction
Smiles
CCC1=C (N=C (C (=N1) C (=O) N) NC2=CC (=C (C=C2) N3CCN (CC3) C (=O) CNC4=C (C=C (C=C4) S (=O) (=O) NC (=O) C5=C (C=C (C=C5) N6CCN (CC6) CC7=C (CC (CC7) (C) C) C8=CC=C (C=C8) Cl) OC9=CN=C1C (=C9) C=CN1) [N+] (=O) [O-]) OC) NC1CCOCC1
Molecular Formula
C64H73ClN14O10S
Molecular Weight
1265.87
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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